Nextstrain
Business Profile
Core Value Proposition
Nextstrain provides real-time tracking of pathogen evolution.
Target Customer
{"Virologists","Epidemiologists","Public health officials","Citizen scientists","Researchers in research labs","Public health entities"}
Key Differentiator
Open-source toolkit delivering real-time, continually-updated pathogen evolution analyses with in-browser tools (Nextclade) and interactive visualizations (Auspice), plus datasets and narratives shared by labs and public health organizations.
Implementation Timeline
Immediate to short-term value; analyses and visualizations are available in real time as data are loaded and processed, with open-source tooling for quick adaptation.
Pain Points
- 1Slow, non-real-time dissemination of epidemiologically relevant results
- 2Difficulty synthesizing data and findings from multiple research groups into a single, up-to-date view
- 3Need for rapid, interactive surveillance tools to inform public health decision-making
Key Features
- 1Real-time tracking of pathogen evolution and spread
- 2In-browser tool Nextclade for phylogenetic placement, clade assignment, mutation calling and sequence quality checks
- 3Open-source bioinformatics workflows and visualization tooling (Augur, Auspice, Nextstrain CLI, Nextclade.us)
- 4Continually updated datasets and narratives from research labs and public health entities
- 5Interactive data visualizations and pipelines to synthesize data across groups
Target Customer Industries
Decision Makers
- 1Virologist
- 2Epidemiologist
- 3Public Health Official
- 4Laboratory Director
- 5Bioinformatician
- 6Data Scientist
Client Results
- 1Real-time insights into pathogen evolution and geographic/spread patterns
- 2Up-to-date data visualizations to support surveillance and public health response
- 3Faster dissemination and sharing of analyses across research and public health communities
Competitive Advantages
- 1Open-source, freely accessible toolkit and datasets
- 2Real-time, continually updated pathogen analyses
- 3In-browser analyses (Nextclade) and interactive visualizations (Auspice)
- 4Ability to share datasets and narratives across laboratories and public health organizations
- 5No vendor lock-in and community-driven data sharing
Key Benefits
Case Studies & Success Stories
SARS-CoV-2 – Ongoing evolution and spread
Continual analyses of SARS-CoV-2 evolution and geographic spread
Mpox in the DRC – INRB analysis of ongoing mpox clade I outbreak in the DRC
Analysis of mpox clade I outbreak in the Democratic Republic of the Congo by INRB
H5N1 cattle outbreak – USA genotype B3.13
Influenza H5N1 cattle outbreak in the USA (genotype B3.13)
HPAI outbreak – North America
Highly pathogenic avian influenza in North America
Seasonal influenza – evolution and antigenic drift
Seasonal influenza evolution and antigenic drift analyses
Additional Product Information
Product Description
An open-source project to harness the scientific and public health potential of pathogen genome data
Target Market
Researchers in genomics and public health, public health agencies, laboratories, and academic institutions seeking real-time genomic epidemiology and interactive visualization tools
Unique Value Proposition
Open-source, real-time genomic epidemiology platform with interactive visualizations and shared datasets that enable rapid, collaborative surveillance and analysis across the global research and public health community
Technical Requirements
Web-based tools and open-source pipelines (Nextclade, Auspice, Augur, Nextstrain CLI) with data accessible via online visualizations; software components hosted on public repositories
Pricing Model
Not specified in the provided content; described as an open-source project
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