RCSB PDB (RCSB Protein Data Bank)

Business Profile

Core Value Proposition

RCSB PDB provides access and tools for exploration, visualization, and analysis of macromolecular structures, including experimentally-determined 3D structures from the PDB archive, Integrative 3D Structures, and Computed Structure Models (CSM) from AlphaFold DB and ModelArchive.

Target Customer

Researchers, educators, students, and developers who work with structural biology data; users range from students to specialized scientists.

Key Differentiator

Comprehensive, standards-based platform with deposition, validation, advanced search, multiple visualization and analysis tools, educational resources, and integration with AlphaFold/ModelArchive, all under wwPDB governance and hosted services.

Pain Points

1Accessing a centralized, standards-aligned repository of 3D structural data (experimental, integrative, and computed).
2Searching and exploring structures by annotations, sequence, structure, or function.
3Deposition, validation, and dissemination of macromolecular structures with supported workflows.

Key Features

1Mol* (MolStar) 3D visualization for structures and ligand binding sites, accessible from structure summary pages.
2Advanced search and browse by annotations, with sequence, structure, and function queries.
3Deposition and validation workflows (wwPDB OneDep System; Validation Server/API) for structure data.
4Sequence Annotations Viewer and Genome View for contextual visualization of protein features and genome mappings.
5Web APIs and download services for programmatic access to data, coordinates, sequences, and ligands.

Target Customer Industries

Client Results

1242,573 Structures from the PDB archive
21,068,577 Computed Structure Models (CSM)
3Access to experimental, integrative, and computed PDB data; visualization, search, and download capabilities

Competitive Advantages

1Integrated, end-to-end platform supporting deposition, validation, and access to PDB data.
2Rich visualization and analysis tools (Mol*; sequence and genome views; pairwise/structure alignment; EPPIC, MeSH Network Explorer, etc.).
3Educational resources (PDB-101) and outreach materials to support teaching and learning.
4Cloud-hosted infrastructure (AWS) for scalable data delivery and worldwide access.
5Continuous updates and integration with external resources (AlphaFold DB, ModelArchive).

Key Benefits

1Unified access to experimental, integrative, and computed structural data

2Powerful visualization and analysis capabilities

3Advanced search and programmatic access via APIs

4Deposition, validation, and data dissemination workflows

5Educational resources and community-facing content (PDB-101)

Additional Product Information

Product Description

A web-based platform that curates and annotates PDB data, providing tools for searching, visualizing, downloading, and analyzing 3D macromolecular structures, including experimental, integrative, and computed models, with deposition/validation workflows and educational resources.

Target Market

Researchers, educators, students, and developers in life sciences, computational biology, biotechnology, and related fields who need robust access to structural data

Unique Value Proposition

A centralized, standards-driven repository with rich visualization, extensive tooling, deposition/validation workflows, APIs, and educational content, backed by wwPDB and AWS infrastructure.

Technical Requirements

Web-based platform requiring a modern web browser; data served from AWS; Mol* viewer available on structure pages; Web APIs for data access.

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